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Microbial resequencing tool, NimbleGen System
July 2005
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NimbleGen Systems is offering a new rapid microbial resequencing tool with the ability to identify the genetic variation between a reference genome and closely related microbial isolates. This method is important for industrial fermentation, homeland security, antibiotic resistance, and pathogen studies. NimbleGen's method surveys an entire microbial genome to pinpoint genetic changes, down to the single nucleotide level. NimbleGen claims the overall false-positive rate is typically less than one false call per one million bases analyzed. NimbleGen uses its high-capacity 385,000-probe microarrays and isothermal probe selection strategy to enable consistent detection of sequence differences between genomes. NimbleGen's Maskless Array Synthesis (MAS) platform provides for a rapid and low-cost method to finely tile across the regions of genomic difference. Other array platforms require longer lead times to fabricate the arrays or more arrays to meet the capacity requirements.
 
NimbleGen
608.218.7600

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