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Signal Transduction Protein Array, Sigma-Aldrich
July 2006
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Sigma-Aldrich announced the latest addition to its functional protein array product line, the Panorama Human Signal Transduction Protein Array. The new array allows researchers to study the function of key protein families by performing parallel assays for selectivity with other proteins, antibodies, peptides, kinases and drug candidates. Developed in conjunction with Procognia Ltd., and licensed exclusively through Sigma-Aldrich, the Signal Transduction array contains 259 full-length proteins that are involved in key cellular processes including proliferation, differentiation and apoptosis. The Panorama Array employs a unique fusion tag that has been shown to confer protein functionality and that also serves to select, tether and uniformly orient proteins on a streptavidin-coated glass slide. This technology offers the unique advantage of allowing proteins to behave in a sterically unencumbered manner, thereby increasing the potential for acquiring data that is more closely representative of native physiological states.
 
Sigma-Aldrich
800.325.5832
http://sigma-aldrich.com/arrays

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